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Restylane Refyne

Restylane Refyne is a hyaluronic acid-based dermal filler used to minimize the appearance of expression lines, such as the nasolabial folds, by providing the skin with support in those areas. Repeated facial movements or expressions over time, such as smiling or wincing, cause these wrinkles to develop. 

Increased volume

Tissue hydration

Longer-lasting improvements

Increased volume
Tissue hydration
Longer-lasting improvements
Results with Flexibility
Results with Flexibility

Facial expressions are a natural part of every day. Most people don’t even notice how often they make facial expressions. These movements are a visual manifestation of the millions of neurons firing in our brains at any given moment. However, these repeated facial expressions can lead to the formation of nasolabial folds, which run from both sides of the nose to the corners of the mouth. These folds become more visible as we age, due to lack of collagen, shifting of fatty tissues, and the wearing away of ligaments under the skin. Restylane Refyne was developed to increase support in these areas while at the same time maintaining the flexibility necessary to continue making facial expressions. 

How it Works

Restylane Refyne is made with hyaluronic acid, an ingredient that offers many benefits. Hyaluronic acid is very hydrophilic, which means it attracts water.
When injected into areas with visible wrinkles, Restylane Refyne provides immediate support to minimize the appearance of nasolabial folds.
Because hyaluronic acid attracts moisture to the treatment site, the results will include more volume, hydration of surrounding tissues, and longer-lasting improvements.
Hyaluronic acid is a popular ingredient in dermal fillers because it is naturally produced by the human body, thereby minimizing the risk of adverse reactions after treatment.
Restylane Refyne is also made with XpressHAn technology, which facilitates cross-linking among the hyaluronic acid molecules to create a gel that is highly flexible and better able to accommodate facial movements.

Treatment Areas

Facial Expression Lines

Restylane Refyne was created to minimize the appearance of facial expression lines, such as the nasolabial folds.


This filler helps clients achieve a balance between increased tissue support under the wrinkle and flexibility, delivering improvements that are subtle and natural.


Restylane Refyne results can last for several months and should be maintained with touch-up treatments.

Frequently Asked Questions
What can I expect from my injection?
We recommend clients first attend a consultation before undergoing treatment with Restylane Refyne. During the consultation, our specialist will discuss cosmetic concerns and help the client set realistic aesthetic goals. In addition, the consultation will help clients determine whether Restylane Refyne is the best choice for them or if another injectable may better achieve aesthetic goals.

Injection of Restylane Refyne is painless, with minimal discomfort. Before making the injections, the physician may apply a topical anesthetic to ensure comfort.
Are there any side effects?
Like any dermal filler, Restylane Refyne may cause temporary side effects, such as redness and inflammation at the injection site. This is due to the body’s immune response. Side effects are typically mild and resolve within a few days. Clients are welcome to apply makeup to cover up any temporary redness.

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